Glucagon is produced by which cells in the pancreas?

Glucagon is a hormone that plays a crucial role in glucose metabolism, specifically in raising blood glucose levels. It is produced by alpha cells, which are one of the main types of cells found in the islets of Langerhans in the pancreas. When the body’s blood sugar levels are low, alpha cells secrete glucagon, prompting the liver to convert stored glycogen into glucose and release it into the bloodstream. This process is essential for maintaining energy levels and proper metabolic function.

The other cell types in the pancreas have different roles. Beta cells are responsible for producing insulin, which lowers blood glucose levels. Delta cells secrete somatostatin, which helps regulate the endocrine system and inhibit the release of both insulin and glucagon. Epsilon cells produce ghrelin, a hormone that regulates appetite and energy balance. Understanding the specific functions of these different cell types is key to comprehending how hormonal regulation of blood sugar occurs in the body.