Which condition does Herpes zoster primarily affect?

Herpes zoster, commonly known as shingles, primarily affects the nerves. This condition results from the reactivation of the varicella-zoster virus, which also causes chickenpox. After an individual has had chickenpox, the virus resides in the nerve roots of the spinal cord and can become reactivated years later, leading to herpes zoster.

When the virus reactivates, it travels down the sensory nerves to the skin, causing a painful rash and blisters that typically follow the path of the affected nerves. This is why the primary impact is on the nervous system, resulting in symptoms that are often localized to a specific area of the body where the nerves are affected. Understanding this aspect of herpes zoster is crucial for effective diagnosis and treatment, as the nerve involvement is directly responsible for the pain, itching, and discomfort experienced by the patient.