Which one of the following enzymes is NOT produced in the pancreas?

The correct answer is that pepsin is not produced in the pancreas. Pepsin is an enzyme primarily produced in the stomach. It is secreted as an inactive precursor, pepsinogen, and becomes active in the acidic environment of the stomach, where it plays a crucial role in the digestion of proteins.

In contrast, the pancreas produces lipase, trypsin, and amylase. Lipase is responsible for the breakdown of fats into fatty acids and glycerol, trypsin aids in protein digestion by cleaving peptide bonds, and amylase is involved in the digestion of carbohydrates, breaking down starches into simpler sugars. Each of these enzymes is secreted into the small intestine, where they help facilitate digestion, but pepsin remains localized to the stomach and is not produced by the pancreas.